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Ligand · AAX

AAX · N-(cyclopropylmethyl)-4-(methyloxy)-3-({5-[3-(3-pyridinyl)phenyl]-1,3-oxazol-2-yl}amino)benzenesulfonamide

AAX, N-(cyclopropylmethyl)-4-(methyloxy)-3-({5-[3-(3-pyridinyl)phenyl]-1,3-oxazol-2-yl}amino)benzenesulfonamide (C25 H24 N4 O4 S, 476.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…

Component
AAX
Formula
C25 H24 N4 O4 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

AAX in 2 structures; the first of them:

  • 1Y6B · Crystal structure of VEGFR2 in complex with a 2-anilino-5-aryl-oxazole inhibitor · AAX A201 · binds LEU838, GLY839, ARG840, GLY841, VAL846, GLU848, ALA864, VAL865 and 12 more
  • 1Y6B · Crystal structure of VEGFR2 in complex with a 2-anilino-5-aryl-oxazole inhibitor · AAX A201 · binds LEU838, GLY839, ARG840, GLY841, VAL846, GLU848, ALA864, VAL865 and 12 more

Residues it binds most

VAL 2, GLU 2, GLY 2, LEU 2, LYS 2, PHE 2, ALA 2, ARG 2, ASN 2, CYS 2 (residue and the binding sites it lines).

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