GL1X · GenesisL1 explorer

Ligand · A8T

A8T · 2-{6-[4-(4-benzylphthalazin-1-yl)piperazin-1-yl]pyridin-3-yl}propan-2-ol

A8T, 2-{6-[4-(4-benzylphthalazin-1-yl)piperazin-1-yl]pyridin-3-yl}propan-2-ol (C27 H29 N5 O, 439.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
A8T
Formula
C27 H29 N5 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

A8T in 2 structures; the first of them:

  • 4QIM · Structure of the human smoothened receptor in complex with ANTA XV · A8T A1201 · binds ILE215, ASN219, PRO220, LEU221, PHE222, MET230, TRP281, MET301 and 19 more
  • 4QIM · Structure of the human smoothened receptor in complex with anta xv · A8T A1201 · binds ILE215, ASN219, PRO220, LEU221, PHE222, MET230, TRP281, MET301 and 19 more

Residues it binds most

LEU 2, PHE 2, ASN 2, ASP 2, GLU 2, ILE 2, MET 2, PRO 2, ARG 2, GLN 2 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.