GL1X · GenesisL1 explorer

Ligand · A4M

A4M · [3-(6-amino-2-methyl-9H-purin-9-yl)azetidin-1-yl]{5-[(4-cycloheptylpiperazin-1-yl)methyl]-1-methyl-1H-pyrazol-3-yl}methanone

A4M, [3-(6-amino-2-methyl-9H-purin-9-yl)azetidin-1-yl]{5-[(4-cycloheptylpiperazin-1-yl)methyl]-1-methyl-1H-pyrazol-3-yl}methanone (C26 H38 N10 O, 506.7 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
A4M
Formula
C26 H38 N10 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

A4M in 2 structures; the first of them:

  • 5WCG · SET and MYND Domain Containing protein 2 · A4M A504 · binds GLY16, LYS17, GLU135, HIS137, CYS181, ASN182, GLY183, PHE184 and 9 more
  • 5WCG · Set and mynd domain containing protein 2 · A4M A504 · binds GLY16, LYS17, HIS137, CYS181, ASN182, GLY183, PHE184, ALA203 and 5 more

Residues it binds most

ASN 2, GLY 2, HIS 2, PHE 2, TYR 2, CYS 2, ALA 2, LYS 2, GLU 1, SER 1 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • UNX · Unknown atom or ion
  • DMS · Dimethyl sulfoxide
  • TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.