GL1X · GenesisL1 explorer

Ligand · A1L25

A1L25 · (2~{S})-2-[[4-[[2,4-bis(azanyl)-6-oxidanylidene-1~{H}-pyrimidin-5-yl]carbamoylamino]-3-methyl-phenyl]carbonylamino]pentanedioic acid

A1L25, (2~{S})-2-[[4-[[2,4-bis(azanyl)-6-oxidanylidene-1~{H}-pyrimidin-5-yl]carbamoylamino]-3-methyl-phenyl]carbonylamino]pentanedioic acid (C18 H21 N7 O7, 447.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (2 PDB…

Component
A1L25
Formula
C18 H21 N7 O7
Class
ligand
Structures
2
PDB entries
2

Binding sites

A1L25 in 2 structures; the first of them:

  • 9ITA · Human MTHFD2 in complex with compound 16d · A1L25 A401 · binds SER83, TYR84, ASN87, LYS88, LEU130, VAL131, GLN132, LEU133 and 13 more
  • 9IUO · Human MTHFD1 in complex with compound 16d · A1L25 A401 · binds TYR52, VAL55, LYS56, LEU98, VAL99, GLN100, LEU101, ASP125 and 10 more

Residues it binds most

GLY 6, LEU 6, VAL 6, PRO 6, ILE 6, THR 6, ASP 6, GLN 6, LYS 6, TYR 6 (residue and the binding sites it lines).

Found with

  • NAD · Nicotinamide-adenine-dinucleotide
  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate
  • PO4 · Phosphate ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.