A1APQ · (4S,5R,7R,11aP)-10-{[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl}-N~3~-methyl-6,7-dihydro-5H-5,7-methanoimidazo[2,1-a][2]benzazepine-2,3-dicarboxamide

Binding sites

A1APQ in 1 structure; the first of them:

• 9BJ1 · Crystal structure of inhibitor GNE-6893 bound to HPK1 · A1APQ B307 · binds LEU23, GLY24, GLY25, GLY26, VAL31, ALA44, LYS46, GLU62 and 15 more

Residues it binds most

GLY 1, ALA 1, LEU 1, GLU 1, PHE 1, VAL 1, ASP 1, CYS 1, ILE 1, LYS 1 (residue and the binding sites it lines).

Found with

• A1APR · (9S)-2-{[(6P)-8-amino-6-(5-amino-4-methylpyridin-3-yl)-7-fluoroisoquinolin-3-yl]amino}-6-methyl-5,6-dihydro-4H-pyrazolo[1,5-d][1,4]diazepin-7(8H)-one
• NA · Sodium ion
• DMS · Dimethyl sulfoxide
• EDO · 1,2-ethanediol
• MES · 2-(N-morpholino)-ethanesulfonic acid
• PEG · Di(hydroxyethyl)ether