GL1X · GenesisL1 explorer

Ligand · 9ZK

9ZK · (4~{R},7~{R},10~{S},13~{S},15~{E},19~{S})-10-(4-azanylbutyl)-4-(4-hydroxyphenyl)-7-(1~{H}-indol-3-ylmethyl)-8,13,15,19-tetramethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone

9ZK, (4~{R},7~{R},10~{S},13~{S},15~{E},19~{S})-10-(4-azanylbutyl)-4-(4-hydroxyphenyl)-7-(1~{H}-indol-3-ylmethyl)-8,13,15,19-tetramethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone (C38 H51 N5 O6, 673.8 g/mol), in the MolNFT…

Component
9ZK
Formula
C38 H51 N5 O6
Class
ligand
Structures
6
PDB entries
4

Binding sites

9ZK in 6 structures; the first of them:

  • 5OOC · Cryo-EM structure of jasplakinolide-stabilized F-actin in complex with ADP · 9ZK A402 · binds ILE75, PRO112, ALA114, ASP179
  • 5OOD · Cryo-EM structure of jasplakinolide-stabilized F-actin in complex with ADP-Pi · 9ZK A403 · binds ILE75, PRO112, ALA114, ARG177, ASP179
  • 5OOC · Cryo-EM structure of jasplakinolide-stabilized F-actin in complex with ADP · 9ZK A402 · binds ILE75, PRO112, ALA114, ASP179
  • 5OOD · Cryo-EM structure of jasplakinolide-stabilized F-actin in complex with ADP-pi · 9ZK A403 · binds ILE75, PRO112, ALA114, ARG177, ASP179
  • 6T23 · Cryo-EM structure of jasplakinolide-stabilized F-actin (aged) · 9ZK A379 · binds ILE75, LEU110, PRO112, ALA114, ASN115, ARG177, ASP179, ILE287
  • 6T24 · Cryo-EM structure of jasplakinolide-stabilized F-actin (aged) · 9ZK A379 · binds ILE75, LEU110, PRO112, ALA114, ARG177, ASP179, ILE287

Residues it binds most

ILE 30, ARG 28, LEU 26, VAL 24, ALA 30, ASP 30, PRO 30, GLN 24, GLU 24, GLY 24 (residue and the binding sites it lines).

Found with

  • ADP · Adenosine-5'-diphosphate
  • MG · Magnesium ion
  • PO4 · Phosphate ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.