GL1X · GenesisL1 explorer

Ligand · 9U4

9U4 · 3-[7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl]-N-methyl-1-(oxan-4-yl)-1,4, 6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxamide

9U4, 3-[7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl]-N-methyl-1-(oxan-4-yl)-1,4, 6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxamide (C27 H33 F2 N7 O2, 525.6 g/mol), in the MolNFT structures on…

Component
9U4
Formula
C27 H33 F2 N7 O2
Class
ligand
Structures
4
PDB entries
2

Binding sites

9U4 in 4 structures; the first of them:

  • 5VZS · BRD4-BD1 in complex with Cpd19 (3-(7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dih… · 9U4 A202 · binds TRP81, PRO82, PHE83, VAL87, LEU92, LEU94, TYR97, TYR139 and 2 more
  • 5W0E · CREBBP bromodomain in complex with Cpd19 (3-(7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-y… · 9U4 A1201 · binds PRO1106, LEU1109, PRO1110, PHE1111, VAL1115, LEU1120, ILE1122, TYR1125 and 6 more
  • 5VZS · BRD4-BD1 in complex with CPD19 (3-(7-(difluoromethyl)-6-(1-methyl-1H… · 9U4 A202 · binds TRP81, PRO82, PHE83, VAL87, LEU92, LEU94, TYR97, TYR139 and 2 more
  • 5W0E · Crebbp bromodomain in complex with CPD19 (3-(7-(difluoromethyl)-6-(1… · 9U4 A1201 · binds PRO1106, LEU1109, PRO1110, PHE1111, VAL1115, LEU1120, ILE1122, ASN1168 and 3 more

Residues it binds most

LEU 6, PHE 6, PRO 6, TYR 4, VAL 6, ASN 6, ILE 6, TRP 4, ARG 2, GLN 2 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.