Ligand · 9OG

9OG · 4-(2-{[(2-amino-4-methylquinolin-7-yl) methyl]amino}ethyl)benzonitrile

9OG, 4-(2-{[(2-amino-4-methylquinolin-7-yl) methyl]amino}ethyl)benzonitrile (C20 H20 N4, 316.4 g/mol), in the MolNFT structures on GenesisL1: bound in 5 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the…

Component: 9OG
Formula: C20 H20 N4
Class: ligand
Structures: 5
PDB entries: 3

Binding sites

9OG in 5 structures; the first of them:

5VV9 · Structure of bovine endothelial nitric oxide synthase heme domain in complex with… · 9OG A503 · binds VAL106, LEU107, PRO336, VAL338, PHE355, SER356, GLY357, TRP358 and 6 more
5VVD · Structure of human endothelial nitric oxide synthase heme domain in complex with… · 9OG A503 · binds VAL104, PHE105, PRO334, VAL336, PHE353, GLY355, TRP356, TYR357 and 4 more
5VUT · Structure of rat neuronal nitric oxide synthase heme domain in complex with… · 9OG A803 · binds PRO565, VAL567, PHE584, TRP587, TYR588, GLU592, TRP678, TRP306
5VV9 · Structure of bovine endothelial nitric oxide synthase heme domain in complex with… · 9OG A503 · binds LEU107, PRO336, VAL338, PHE355, TRP358, TYR359, MET360, GLU363 and 3 more
5VVD · Structure of human endothelial nitric oxide synthase heme domain in complex with… · 9OG A503 · binds PHE105, PRO334, VAL336, PHE353, TRP356, TYR357, GLU361, TRP74

Residues it binds most

TRP 14, VAL 14, PHE 14, TYR 14, GLU 14, PRO 12, MET 9, GLY 5, LEU 4, SER 1 (residue and the binding sites it lines).

Found with

H4B · 5,6,7,8-tetrahydrobiopterin
HEM · Protoporphyrin IX containing Fe
ZN · Zinc ion
GOL · Glycerol
GD · Gadolinium atom
CL · Chloride ion
BTB · 2-[bis-(2-hydroxy-ethyl)-amino]-2-hydroxymethyl-propane-1,3-diol
ACT · Acetate ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.