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Ligand · 971

971 · 1-methyl-4-{3-[6-(piperazin-1-yl)pyridin-2-yl]-1H-pyrazolo[3,4-c]pyridin-5-yl}piperazin-2-one

971, 1-methyl-4-{3-[6-(piperazin-1-yl)pyridin-2-yl]-1H-pyrazolo[3,4-c]pyridin-5-yl}piperazin-2-one (C20 H24 N8 O, 392.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
971
Formula
C20 H24 N8 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

971 in 2 structures; the first of them:

  • 5V80 · PIM1 kinase in complex with Cpd1 (1-methyl-4-(3-(6-(piperazin-1-yl)pyridin-2-yl)-1H-pyrazo… · 971 A402 · binds LEU44, PHE49, VAL52, ALA65, LYS67, ILE104, LEU120, GLU121 and 9 more
  • 5V80 · PIM1 kinase in complex with CPD1 (1-methyl-4-(3-(6-(piperazin-1-yl)… · 971 A402 · binds LEU44, PHE49, VAL52, ALA65, LYS67, LEU120, GLU121, ARG122 and 6 more

Residues it binds most

LEU 2, ASP 2, VAL 2, ILE 2, ALA 2, ARG 2, ASN 2, GLU 2, LYS 2, PHE 2 (residue and the binding sites it lines).

Found with

  • PO4 · Phosphate ion

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