Ligand · 965
965 · [3-(3-{[2-chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino}propoxy)phenyl]acetic acid
965, [3-(3-{[2-chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino}propoxy)phenyl]acetic acid (C33 H31 Cl F3 N O3, 582.0 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB entries). Every binding site with its…
- Component
- 965
- Formula
- C33 H31 Cl F3 N O3
- Class
- ligand
- Structures
- 6
- PDB entries
- 3
Binding sites
965 in 6 structures; the first of them:
- 1PQ6 · Human lxr beta hormone receptor / GW3965 complex · 965 A1500 · binds ASN239, PHE268, PHE271, LEU274, ALA275, SER278, GLU281, ILE309 and 20 more
- 3IPQ · X-ray structure of GW3965 synthetic agonist bound to the LXR-alpha · 965 A801 · binds PHE254, PHE257, THR258, LEU260, ALA261, VAL263, SER264, GLU267 and 22 more
- 4NQA · Crystal structure of liganded hRXR-alpha/hLXR-beta heterodimer on DNA · 965 B501 · binds ASN239, PHE268, PHE271, THR272, LEU274, ALA275, ILE277, SER278 and 21 more
- 1PQ6 · Human lxr beta hormone receptor / GW3965 complex · 965 A1500 · binds ASN239, PHE268, PHE271, LEU274, ALA275, SER278, GLU281, ILE309 and 20 more
- 3IPQ · X-ray structure of GW3965 synthetic agonist bound to the lxr-alpha · 965 A801 · binds PHE254, PHE257, THR258, LEU260, ALA261, VAL263, SER264, GLU267 and 22 more
- 4NQA · Crystal structure of liganded hrxr-ALPHA/HLXR-beta heterodimer on DNA · 965 B501 · binds ASN239, PHE268, PHE271, THR272, LEU274, ALA275, ILE277, SER278 and 21 more
Residues it binds most
PHE 12, LEU 12, ILE 12, GLU 12, THR 12, SER 12, VAL 12, ALA 12, ARG 12, GLN 12 (residue and the binding sites it lines).
Found with
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