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Ligand · 960

960 · 1-[(6-chloroimidazo[1,2-b]pyridazin-3-yl)sulfonyl]-6-(1-methyl-1H-pyrazol-4-yl)-1H-pyrazolo[4,3-b]pyridine

960, 1-[(6-chloroimidazo[1,2-b]pyridazin-3-yl)sulfonyl]-6-(1-methyl-1H-pyrazol-4-yl)-1H-pyrazolo[4,3-b]pyridine (C16 H11 Cl N8 O2 S, 414.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…

Component
960
Formula
C16 H11 Cl N8 O2 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

960 in 2 structures; the first of them:

  • 5Z0S · Crystal structure of FGFR1 kinase domain in complex with a novel inhibitor · 960 A801 · binds LEU484, GLY485, PHE489, VAL492, ALA512, LYS514, GLU531, ILE545 and 10 more
  • 5Z0S · Crystal structure of FGFR1 kinase domain in complex with a novel inhibitor · 960 A801 · binds LEU484, GLY485, PHE489, VAL492, ALA512, LYS514, ILE545, VAL561 and 9 more

Residues it binds most

ALA 4, ASN 4, LEU 4, VAL 4, GLU 4, ARG 4, ASP 4, GLY 4, ILE 4, LYS 4 (residue and the binding sites it lines).

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