GL1X · GenesisL1 explorer

Ligand · 953

953 · 5-(2-aminopyrimidin-4-yl)-2-[2-chloro-5-(trifluoromethyl)phenyl]-1H-pyrrole-3-carboxamide

953, 5-(2-aminopyrimidin-4-yl)-2-[2-chloro-5-(trifluoromethyl)phenyl]-1H-pyrrole-3-carboxamide (C16 H11 Cl F3 N5 O, 381.7 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
953
Formula
C16 H11 Cl F3 N5 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

953 in 2 structures; the first of them:

  • 4D0X · Pyrrole-3-carboxamides as potent and selective JAK2 inhibitors · 953 A2132 · binds LEU855, GLY856, LYS857, GLY858, GLY861, SER862, VAL863, ALA880 and 14 more
  • 4D0X · Pyrrole-3-carboxamides as potent and selective JAK2 inhibitors · 953 A2132 · binds LEU855, GLY856, LYS857, GLY858, GLY861, SER862, VAL863, ALA880 and 14 more

Residues it binds most

GLY 2, LEU 2, ASP 2, LYS 2, SER 2, VAL 2, ALA 2, ARG 2, ASN 2, GLU 2 (residue and the binding sites it lines).

Found with

  • GOL · Glycerol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.