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Ligand · 914

914 · [(2R,5R)-5-(6-aminopurin-9-yl)-4-fluoro-2,5-dihydrofuran-2-yl]oxymethyl-[hydroxy(phosphonooxy)phosphoryl]oxy-phosphinic acid

914, [(2R,5R)-5-(6-aminopurin-9-yl)-4-fluoro-2,5-dihydrofuran-2-yl]oxymethyl-[hydroxy(phosphonooxy)phosphoryl]oxy-phosphinic acid (C10 H13 F N5 O11 P3, 491.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry).…

Component
914
Formula
C10 H13 F N5 O11 P3
Class
ligand
Structures
2
PDB entries
1

Binding sites

914 in 2 structures; the first of them:

  • 3KK1 · HIV-1 reverse transcriptase-DNA complex with nuceotide inhibitor GS-9148-diphosphate… · 914 A825 · binds ILE63, LYS65, LYS70, ARG72, LEU74, ASP110, VAL111, GLY112 and 10 more
  • 3KK1 · HIV-1 reverse transcriptase-DNA complex with nuceotide inhibitor gs- 9148-diphosphate… · 914 A825 · binds ILE63, LYS65, LYS70, ARG72, LEU74, ASP110, VAL111, GLY112 and 10 more

Residues it binds most

ASP 2, LYS 2, ALA 2, ARG 2, DG 2, DOC 2, DT 2, GLN 2, GLY 2, ILE 2 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • SO4 · Sulfate ion

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