Ligand · 904
904 · N'-(3-{[5-(2-cyclopropylpyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)-N-ethyl-N-methylsulfuric diamide
904, N'-(3-{[5-(2-cyclopropylpyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)-N-ethyl-N-methylsulfuric diamide (C24 H22 F2 N6 O3 S, 512.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…
- Component
- 904
- Formula
- C24 H22 F2 N6 O3 S
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
904 in 2 structures; the first of them:
- 4XV1 · B-Raf Kinase V600E oncogenic mutant in complex with PLX7904 · 904 A801 · binds ILE463, VAL471, ALA481, VAL482, LYS483, LEU505, LEU514, LEU515 and 11 more
- 4XV1 · B-RAF kinase V600E oncogenic mutant in complex with PLX7904 · 904 A801 · binds ILE463, VAL471, ALA481, VAL482, LYS483, LEU505, LEU514, LEU515 and 11 more
Residues it binds most
LEU 2, PHE 2, GLY 2, ILE 2, VAL 2, ALA 2, ASP 2, CYS 2, GLN 2, LYS 2 (residue and the binding sites it lines).
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