GL1X · GenesisL1 explorer

Ligand · 8ZZ

8ZZ · ~{N}-(2-chloranyl-6-methyl-phenyl)-2-[[3-[[(3~{R}, 4~{R})-3-fluoranylpiperidin-4-yl]carbamoyl]phenyl]amino]-1,3-thiazole-5-carboxamide

8ZZ, ~{N}-(2-chloranyl-6-methyl-phenyl)-2-[[3-[[(3~{R}, 4~{R})-3-fluoranylpiperidin-4-yl]carbamoyl]phenyl]amino]-1,3-thiazole-5-carboxamide (C23 H23 Cl F N5 O2 S, 488.0 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (2…

Component
8ZZ
Formula
C23 H23 Cl F N5 O2 S
Class
ligand
Structures
3
PDB entries
2

Binding sites

8ZZ in 3 structures; the first of them:

  • 5NK2 · Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with Compound 2b · 8ZZ A1001 · binds ILE619, VAL627, ALA644, ILE645, LYS646, GLU663, MET667, ILE676 and 10 more
  • 5NK2 · Crystal structure of ephrin A2 (EPHA2) receptor protein kinase with compound 2B · 8ZZ A1001 · binds ILE619, VAL627, ALA644, ILE645, LYS646, GLU663, MET667, ILE676 and 10 more
  • 5NK7 · Crystal structure of ephrin A2 (EPHA2) receptor protein kinase with compound 2A · 8ZZ A1001 · binds ILE619, VAL627, ALA644, ILE645, LYS646, GLU663, MET667, ILE690 and 9 more

Residues it binds most

ILE 3, GLU 3, MET 3, ALA 3, LYS 3, GLY 3, LEU 3, SER 3, THR 3, TYR 3 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.