GL1X · GenesisL1 explorer

Ligand · 8ZL

8ZL · (5S,8R)-N,N-dimethyl-8-[[(2S)-1-[4-(methylamino)-4-oxidanylidene-butanoyl]pyrrolidin-2-yl]carbonylamino]-7,11-bis(oxidanylidene)-10-oxa-3-thia-6-azabicyclo[10.4.0]hexadeca-1(12),13,15-triene-5-carboxamide

8ZL, (5S,8R)-N,N-dimethyl-8-[[(2S)-1-[4-(methylamino)-4-oxidanylidene-butanoyl]pyrrolidin-2-yl]carbonylamino]-7,11-bis(oxidanylidene)-10-oxa-3-thia-6-azabicyclo[10.4.0]hexadeca-1(12),13,15-triene-5-carboxamide (C26 H35 N5 O7 S, 561.6…

Component
8ZL
Formula
C26 H35 N5 O7 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

8ZL in 2 structures; the first of them:

  • 7Q6Q · Keap1 compound complex · 8ZL A701 · binds TYR334, SER363, GLY364, ARG380, ASN382, ARG415, GLY462, ARG483 and 12 more
  • 7Q6Q · KEAP1 compound complex · 8ZL A701 · binds TYR334, SER363, GLY364, ASN382, ARG415, ARG483, GLY509, TYR525 and 9 more

Residues it binds most

GLY 2, SER 2, TYR 2, ARG 2, ASN 2, ALA 2, ASP 2, PHE 2, PRO 1 (residue and the binding sites it lines).

Found with

  • NA · Sodium ion
  • CL · Chloride ion

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