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Ligand · 8WP

8WP · 2-[(8S)-4-oxo-2-(trifluoromethyl)-4,5-dihydropyrazolo[1,5-a]pyrazin-6-yl]acetamide

8WP, 2-[(8S)-4-oxo-2-(trifluoromethyl)-4,5-dihydropyrazolo[1,5-a]pyrazin-6-yl]acetamide (C9 H7 F3 N4 O2, 260.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5…

Component
8WP
Formula
C9 H7 F3 N4 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

8WP in 2 structures; the first of them:

  • 7SEC · Crystal structure of human Fibrillarin in complex with compound 1a · 8WP A402 · binds LEU166, GLY167, VAL190, GLU191, PHE192, SER193, ALA217, ALA235 and 4 more
  • 7SEC · Crystal structure of human fibrillarin in complex with compound 1A · 8WP A402 · binds LEU166, GLY167, VAL190, GLU191, PHE192, ASP236, GLN242, ILE245

Residues it binds most

VAL 4, ALA 2, ASP 4, GLN 4, GLU 4, GLY 4, ILE 4, LEU 4, PHE 4, SER 3 (residue and the binding sites it lines).

Found with

  • DMS · Dimethyl sulfoxide
  • FMT · Formic acid

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