GL1X · GenesisL1 explorer

Ligand · 8T5

8T5 · (1~{S},4~{S},7~{R},10~{R})-14-[(3~{S},6~{R},8~{A}~{S})-1'-[(2~{S})-2-acetamido-3-(2-chlorophenyl)propanoyl]-5-oxidanylidene-spiro[1,2,3,8~{a}-tetrahydroindolizine-6,2'-pyrrolidine]-3-yl]carbonyl-2-oxidanylidene-3,14-diazatricyclo[8.4.0.0^{3, 7}]tetradec-8-ene-4-carboxylic acid

8T5, (1~{S},4~{S},7~{R},10~{R})-14-[(3~{S},6~{R},8~{A}~{S})-1'-[(2~{S})-2-acetamido-3-(2-chlorophenyl)propanoyl]-5-oxidanylidene-spiro[1,2,3,8~{a}-tetrahydroindolizine-6,2'-pyrrolidine]-3-yl]carbonyl-2-oxidanylidene-3,14-diazatricyclo[8.4.0…

Component
8T5
Formula
C36 H42 Cl N5 O7
Class
ligand
Structures
2
PDB entries
1

Binding sites

8T5 in 2 structures; the first of them:

  • 5NCF · ENAH EVH1 in complex with Ac-[2-Cl-F]-[ProM-2]-[ProM-4]-OH · 8T5 A201 · binds TYR16, TRP23, LYS69, ASN71, ALA73, THR74, PHE77, GLN79 and 3 more
  • 5NCF · Enah EVH1 in complex with ac-[2-cl-F]-[prom-2]-[prom-4]-oh · 8T5 A201 · binds TYR16, TRP23, LYS69, ASN71, PHE77, GLN79, ARG81, VAL86

Residues it binds most

TRP 4, ASN 4, ARG 4, GLN 4, LYS 4, PHE 4, TYR 4, VAL 4, ALA 2, THR 2 (residue and the binding sites it lines).

Found with

  • NO3 · Nitrate ion
  • SO4 · Sulfate ion
  • GOL · Glycerol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.