Ligand · 8T3
8T3 · N-[3-[(1S,3S,6S)-5-azanyl-3-methyl-4-azabicyclo[4.1.0]hept-4-en-3-yl]-4-fluoranyl-phenyl]-5-chloranyl-pyridine-2-carbox amide
8T3, N-[3-[(1S,3S,6S)-5-azanyl-3-methyl-4-azabicyclo[4.1.0]hept-4-en-3-yl]-4-fluoranyl-phenyl]-5-chloranyl-pyridine-2-carbox amide (C19 H18 Cl F N4 O, 372.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry).…
- Component
- 8T3
- Formula
- C19 H18 Cl F N4 O
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
8T3 in 2 structures; the first of them:
- 4BFD · Crystal structure of bace-1 in complex with chemical ligand · 8T3 A1447 · binds GLY72, GLN73, GLY74, TYR75, LEU91, ASP93, GLY95, SER96 and 11 more
- 4BFD · Crystal structure of bace-1 in complex with chemical ligand · 8T3 A1447 · binds GLY72, GLN73, GLY74, TYR75, LEU91, ASP93, GLY95, SER96 and 11 more
Residues it binds most
GLY 2, ASP 2, ILE 2, SER 2, THR 2, TYR 2, ALA 2, GLN 2, LEU 2, PHE 2 (residue and the binding sites it lines).
Found with
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