Ligand · 8ME
8ME · 3-(4-oxo-3,4-dihydroquinazolin-2-yl)-N-[(1S)-1-(pyridin-2-yl)ethyl]propanamide
8ME, 3-(4-oxo-3,4-dihydroquinazolin-2-yl)-N-[(1S)-1-(pyridin-2-yl)ethyl]propanamide (C18 H18 N4 O2, 322.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å…
- Component
- 8ME
- Formula
- C18 H18 N4 O2
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
8ME in 2 structures; the first of them:
- 4GV0 · Human ARTD3 (PARP3) - Catalytic domain in complex with inhibitor ME0355 · 8ME A601 · binds ASP284, LEU287, VAL288, ASP291, TRP383, HIS384, GLY385, THR386 and 10 more
- 4GV0 · Human ARTD3 (PARP3) - catalytic domain in complex with inhibitor ME0355 · 8ME A601 · binds ASP284, LEU287, VAL288, ASP291, TRP383, HIS384, GLY385, THR386 and 10 more
Residues it binds most
ASP 2, TYR 2, VAL 2, ALA 2, ARG 2, GLU 2, GLY 2, HIS 2, LEU 2, LYS 2 (residue and the binding sites it lines).
Found with
- DMS · Dimethyl sulfoxide
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