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Ligand · 8LT

8LT · (3~{R},4~{R})-1-[(4-methoxyphenyl)methyl]-3-(3-methylbutyl)-3-[4-methylsulfonyl-2-[(2~{S})-1-oxidanylpropan-2-yl]oxy-phenyl]-4-oxidanyl-pyrrolidin-2-one

8LT, (3~{R},4~{R})-1-[(4-methoxyphenyl)methyl]-3-(3-methylbutyl)-3-[4-methylsulfonyl-2-[(2~{S})-1-oxidanylpropan-2-yl]oxy-phenyl]-4-oxidanyl-pyrrolidin-2-one (C27 H37 N O7 S, 519.6 g/mol), in the MolNFT structures on GenesisL1: bound in 1…

Component
8LT
Formula
C27 H37 N O7 S
Class
ligand
Structures
1
PDB entries
1

Binding sites

8LT in 1 structure; the first of them:

  • 7WBS · Crystal structure of HIV-1 protease in complex with lactam derivative 2 · 8LT B101 · binds ARG8, LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32 and 21 more

Residues it binds most

ASP 1, GLY 1, ILE 1, VAL 1, ALA 1, LEU 1, PRO 1, ARG 1 (residue and the binding sites it lines).

Found with

  • GOL · Glycerol

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