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Ligand · 8HG

8HG · 2'-deoxy-8-oxoguanosine

8HG, 2'-deoxy-8-oxoguanosine (C10 H13 N5 O5, 283.2 g/mol), in the MolNFT structures on GenesisL1: bound in 8 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with…

Component
8HG
Formula
C10 H13 N5 O5
Class
ligand
Structures
8
PDB entries
4

Binding sites

8HG in 8 structures; the first of them:

  • 1XQP · Crystal structure of 8-oxoguanosine complexed Pa-AGOG, 8-oxoguanine DNA glycosylase from… · 8HG A257 · binds GLN31, SER58, TYR59, LEU61, GLY65, HIS68, TRP69, LYS140 and 8 more
  • 2A5B · Avidin complexed with 8-oxodeoxyguanosine · 8HG A255 · binds LEU14, SER16, TYR33, THR35, ALA36, TRP70, PHE72, SER73 and 6 more
  • 3F10 · Crystal structure of Clostridium Acetobutylicum 8-oxoguanine DNA glycosylase in complex… · 8HG A293 · binds GLY30, GLN31, PHE33, PHE122, SER125, ASN127, ASN128, ILE130 and 12 more
  • 7OLI · Crystal structure of Pab-AGOG in complex with 8-oxoguanosine · 8HG A301 · binds GLN24, SER51, TYR52, LEU54, TRP62, LYS142, THR143, PHE146 and 6 more
  • 1XQP · Crystal structure of 8-oxoguanosine complexed pa-agog, 8-oxoguanine DNA glycosylase from… · 8HG A257 · binds GLN31, SER58, TYR59, LEU61, GLY65, HIS68, TRP69, LYS140 and 8 more
  • 2A5B · Avidin complexed with 8-oxodeoxyguanosine · 8HG A255 · binds LEU14, SER16, TYR33, THR35, ALA36, TRP70, PHE72, SER73 and 6 more
  • 3F10 · Crystal structure of clostridium acetobutylicum 8-oxoguanine DNA glycosylase in complex… · 8HG A293 · binds GLY30, GLN31, PHE33, PHE122, SER125, ASN127, ASN128, ILE130 and 12 more
  • 7OLI · Crystal structure of pab-agog in complex with 8-oxoguanosine · 8HG A301 · binds GLN24, SER51, TYR52, TRP62, LYS142, PHE146, LYS149, PRO172 and 3 more

Residues it binds most

PHE 10, ASP 10, TRP 8, GLN 8, LYS 8, SER 10, LEU 7, PRO 8, THR 6, TYR 8 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose

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