GL1X · GenesisL1 explorer

Ligand · 8GO

8GO · (2R,4S)-6-ethyl-2-(2-hydroxyethyl)-2,8-dimethyl-4-(2-methylprop-1-enyl)-3,4-dihydropyrano[3,2-C][1, 8]naphthyridin-5-one

8GO, (2R,4S)-6-ethyl-2-(2-hydroxyethyl)-2,8-dimethyl-4-(2-methylprop-1-enyl)-3,4-dihydropyrano[3,2-C][1, 8]naphthyridin-5-one (C21 H28 N2 O3, 356.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
8GO
Formula
C21 H28 N2 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

8GO in 2 structures; the first of them:

  • 7W4Y · Crystal structure of PDE4D catalytic domain complexed with 33a · 8GO A503 · binds TYR159, HIS160, THR271, MET273, ASP318, LEU319, ASN321, TYR329 and 9 more
  • 7W4Y · Crystal structure of PDE4D catalytic domain complexed with 33A · 8GO A503 · binds TYR159, HIS160, THR271, MET273, ASP318, LEU319, ASN321, TYR329 and 9 more

Residues it binds most

MET 4, PHE 4, THR 4, TYR 4, ASN 4, ASP 4, GLN 4, HIS 4, ILE 4, LEU 4 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • ZN · Zinc ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.