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Ligand · 8E3

8E3 · 6-fluoranyl-2-(4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-yl)-1~{H}-benzimidazole-4-carboxamide

8E3, 6-fluoranyl-2-(4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-yl)-1~{H}-benzimidazole-4-carboxamide (C15 H13 F N4 O2, 300.3 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record (1 PDB entry). Every binding site with its residues…

Component
8E3
Formula
C15 H13 F N4 O2
Class
ligand
Structures
1
PDB entries
1

Binding sites

8E3 in 1 structure; the first of them:

  • 5XSU · Novel orally efficacious inhibitors complexed with PARP1 · 8E3 A407 · binds GLU102, HIS201, GLY202, GLY227, TYR228, TYR235, PHE236, ALA237 and 5 more

Residues it binds most

TYR 4, GLU 4, GLY 4, ALA 4, HIS 4, LYS 4, PHE 4, SER 4, ASN 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

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