GL1X · GenesisL1 explorer

Ligand · 8DM

8DM · N-(4-aminobenzene-1-carbonyl)-L-glutamic acid

8DM, N-(4-aminobenzene-1-carbonyl)-L-glutamic acid (C12 H14 N2 O5, 266.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and…

Component
8DM
Formula
C12 H14 N2 O5
Class
ligand
Structures
4
PDB entries
2

Binding sites

8DM in 4 structures; the first of them:

  • 5UIO · structure of DHFR with bound DAP, p-ABG and NADP · 8DM A202 · binds LEU28, ALA29, PHE31, LYS32, ILE50, ARG52, LEU54, PRO55 and 1 more
  • 5UIP · structure of DHFR with bound DAP, p-ABG and NADP · 8DM A201 · binds LEU28, PHE31, LYS32, ILE50, ARG52, LEU54, PRO55, ARG57
  • 5UIO · Structure of DHFR with bound dap, P-abg and NADP · 8DM A202 · binds LEU28, ALA29, PHE31, LYS32, ILE50, ARG52, LEU54, PRO55 and 1 more
  • 5UIP · Structure of DHFR with bound dap, P-abg and NADP · 8DM A201 · binds LEU28, PHE31, LYS32, ILE50, ARG52, LEU54, PRO55, ARG57

Residues it binds most

ARG 12, LEU 12, ILE 12, LYS 12, PHE 12, PRO 10, ALA 4, MET 2, SER 2, THR 2 (residue and the binding sites it lines).

Found with

  • LG3 · Pyrimidine-2,4-diamine
  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate
  • NA · Sodium ion
  • BME · Beta-mercaptoethanol
  • FMT · Formic acid

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.