Ligand · 8BP
8BP · N-[(3R,4R)-4-fluoro-1-{6-[(1-methyl-1H-pyrazol-4-yl)amino]-9-(propan-2-yl)-9H-purin-2-yl}pyrrolidin-3-yl]propanamide
8BP, N-[(3R,4R)-4-fluoro-1-{6-[(1-methyl-1H-pyrazol-4-yl)amino]-9-(propan-2-yl)-9H-purin-2-yl}pyrrolidin-3-yl]propanamide (C19 H26 F N9 O, 415.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…
- Component
- 8BP
- Formula
- C19 H26 F N9 O
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
8BP in 2 structures; the first of them:
- 5UG8 · Crystal structure of the EGFR kinase domain (L858R, T790M, V948R) in complex with a… · 8BP A9001 · binds LEU718, GLY719, SER720, PHE723, VAL726, ALA743, CYS775, MET790 and 11 more
- 5UG8 · Crystal structure of the EGFR kinase domain (L858R, T790M, V948R) in complex with a… · 8BP A9001 · binds LEU718, GLY719, SER720, PHE723, VAL726, ALA743, CYS775, MET790 and 11 more
Residues it binds most
LEU 2, CYS 2, GLY 2, MET 2, PHE 2, ALA 2, ARG 2, ASP 2, GLN 2, PRO 2 (residue and the binding sites it lines).
Found with
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