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Ligand · 835

835 · (3S)-3-(5-azanyl-2-methyl-4-oxidanylidene-quinazolin-3-yl)piperidine-2,6-dione

835, (3S)-3-(5-azanyl-2-methyl-4-oxidanylidene-quinazolin-3-yl)piperidine-2,6-dione (C14 H14 N4 O3, 286.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å…

Component
835
Formula
C14 H14 N4 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

835 in 2 structures; the first of them:

  • 7PSO · Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Avadomide… · 835 C202 · binds PHE49, ASN50, PRO51, PHE56, GLU76, PHE77, SER78, TRP79 and 3 more
  • 7PSO · Cereblon isoform 4 from magnetospirillum gryphiswaldense in complex with avadomide… · 835 C202 · binds ASN50, PRO51, GLU76, PHE77, SER78, TRP79, TRP85, TRP99 and 1 more

Residues it binds most

TRP 2, PHE 2, ASN 2, GLU 2, PRO 2, SER 2, TYR 2 (residue and the binding sites it lines).

Found with

  • EF2 · S-Thalidomide
  • ZN · Zinc ion
  • PO4 · Phosphate ion

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