Ligand · 80U
80U · 1-[(3R)-3-[4-azanyl-3-[3-chloranyl-4-[(1-methylimidazol-2-yl)methoxy]phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one
80U, 1-[(3R)-3-[4-azanyl-3-[3-chloranyl-4-[(1-methylimidazol-2-yl)methoxy]phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one (C24 H25 Cl N8 O2, 493.0 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…
- Component
- 80U
- Formula
- C24 H25 Cl N8 O2
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
80U in 2 structures; the first of them:
- 5GNK · Crystal structure of EGFR 696-988 T790M in complex with LXX-6-34 · 80U A1001 · binds LEU718, GLY719, VAL726, ALA743, ILE744, LYS745, MET766, CYS775 and 15 more
- 5GNK · Crystal structure of EGFR 696-988 T790M in complex with lxx-6-34 · 80U A1001 · binds LEU718, GLY719, VAL726, ALA743, ILE744, LYS745, MET766, CYS775 and 15 more
Residues it binds most
LEU 2, MET 2, ARG 2, ASP 2, CYS 2, ILE 2, ALA 2, GLN 2, GLY 2, LYS 2 (residue and the binding sites it lines).
Found with
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