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Ligand · 7ZT

7ZT · 2-[(3S)-3-{5-[2-(3,5-dimethylphenoxy)pyrimidin-4-yl]-4-(4-iodophenyl)-1H-imidazol-1-yl}pyrrolidin-1-yl]ethan-1-amine

7ZT, 2-[(3S)-3-{5-[2-(3,5-dimethylphenoxy)pyrimidin-4-yl]-4-(4-iodophenyl)-1H-imidazol-1-yl}pyrrolidin-1-yl]ethan-1-amine (C27 H29 I N6 O, 580.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component
7ZT
Formula
C27 H29 I N6 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

7ZT in 2 structures; the first of them:

  • 7RXS · Crystal of BRD4(D1) with 2-[(3S)-3-{5-[2-(3,5-dimethylphenoxy)pyrimidin-4-yl]-4-(4-iodophe… · 7ZT A202 · binds TRP81, PRO82, PHE83, VAL87, LEU92, LEU94, TYR97, MET105 and 6 more
  • 7RXS · Crystal of BRD4(D1) with 2-[(3S)-3-{5-[2-(3,5-dimethylphenoxy)… · 7ZT A202 · binds TRP81, PRO82, PHE83, VAL87, LEU92, LEU94, TYR97, MET105 and 6 more

Residues it binds most

MET 2, LEU 2, TYR 2, ASN 2, CYS 2, ILE 2, PHE 2, PRO 2, TRP 2, VAL 2 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol

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