GL1X · GenesisL1 explorer

Ligand · 7YG

7YG · 3-amino-6-(4-{[2-(dimethylamino)ethyl]sulfamoyl}phenyl)-N-pyridin-3-ylpyrazine-2-carboxamide

7YG, 3-amino-6-(4-{[2-(dimethylamino)ethyl]sulfamoyl}phenyl)-N-pyridin-3-ylpyrazine-2-carboxamide (C20 H23 N7 O3 S, 441.5 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its…

Component
7YG
Formula
C20 H23 N7 O3 S
Class
ligand
Structures
4
PDB entries
2

Binding sites

7YG in 4 structures; the first of them:

  • 4ACC · GSK3b in complex with inhibitor · 7YG A1387 · binds ILE62, PHE67, VAL70, ALA83, LYS85, VAL110, LEU132, ASP133 and 8 more
  • 4ACM · CDK2 in complex with 3-amino-6-(4-{[2-(DIMETHYLAMINO)ETHYL]SULFAMOYL}-phenyl)-N-pyridin-3… · 7YG A1302 · binds ILE10, GLY11, GLY13, VAL18, ALA31, LYS33, VAL64, PHE80 and 12 more
  • 4ACC · GSK3B in complex with inhibitor · 7YG A1387 · binds ILE62, PHE67, VAL70, ALA83, LYS85, VAL110, LEU132, ASP133 and 8 more
  • 4ACM · CDK2 in complex with 3-amino-6-(4-{[2-(DIMETHYLAMINO)ETHYL]SULFAMOYL}… · 7YG A1302 · binds ILE10, GLY11, GLY13, VAL18, ALA31, LYS33, VAL64, PHE80 and 12 more

Residues it binds most

VAL 6, ASP 6, LEU 6, ALA 6, LYS 6, PHE 6, ILE 6, ARG 4, CYS 4, GLN 2 (residue and the binding sites it lines).

Found with

  • DMS · Dimethyl sulfoxide
  • GOL · Glycerol
  • ACE · Acetyl group

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.