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Ligand · 7X8

7X8 · 3-({4-[(5-chloro-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl}amino)benzamide

7X8, 3-({4-[(5-chloro-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl}amino)benzamide (C18 H14 Cl N5 O3, 383.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å…

Component
7X8
Formula
C18 H14 Cl N5 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

7X8 in 2 structures; the first of them:

  • 2VX1 · ephB4 kinase domain inhibitor complex · 7X8 A1889 · binds ILE621, GLY622, VAL629, ALA645, ILE646, LYS647, GLU664, MET668 and 10 more
  • 2VX1 · EPHB4 kinase domain inhibitor complex · 7X8 A1889 · binds ILE621, GLY622, VAL629, ALA645, ILE646, LYS647, GLU664, MET668 and 10 more

Residues it binds most

ILE 2, GLU 2, GLY 2, MET 2, ALA 2, LEU 2, LYS 2, PHE 2, SER 2, THR 2 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion

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