GL1X · GenesisL1 explorer

Ligand · 7TM

7TM · 4-({(3R)-7-cyano-4-[(4-methoxyphenyl)sulfonyl]-1-[(1-methyl-1H-imidazol-5-yl)methyl]-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-3-yl}methyl)phenyl hexylcarbamate

7TM, 4-({(3R)-7-cyano-4-[(4-methoxyphenyl)sulfonyl]-1-[(1-methyl-1H-imidazol-5-yl)methyl]-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-3-yl}methyl)phenyl hexylcarbamate (C36 H42 N6 O5 S, 670.8 g/mol), in the MolNFT structures on GenesisL1…

Component
7TM
Formula
C36 H42 N6 O5 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

7TM in 2 structures; the first of them:

  • 4GTM · FTase in complex with BMS analogue 11 · 7TM B503 · binds TYR131, TYR93, CYS95, LEU96, ALA98, SER99, ARG100, PRO101 and 14 more
  • 4GTM · Ftase in complex with bms analogue 11 · 7TM B503 · binds TYR131, TYR93, CYS95, LEU96, ALA98, SER99, ARG100, PRO101 and 14 more

Residues it binds most

ASP 2, TYR 2, ALA 2, ARG 2, CYS 2, HIS 2, PRO 2, TRP 2, GLY 2, LEU 2 (residue and the binding sites it lines).

Found with

  • FPP · Farnesyl diphosphate
  • ZN · Zinc ion
  • DMS · Dimethyl sulfoxide

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.