Ligand · 7RO
7RO · tert-butyl 6-((2-chloro-4-(dimethylcarbamoyl)phenyl)amino)-2-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridine-1-carboxylate
7RO, tert-butyl 6-((2-chloro-4-(dimethylcarbamoyl)phenyl)amino)-2-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridine-1-carboxylate (C25 H27 Cl N6 O3, 495.0 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB…
- Component
- 7RO
- Formula
- C25 H27 Cl N6 O3
- Class
- ligand
- Structures
- 6
- PDB entries
- 3
Binding sites
7RO in 6 structures; the first of them:
- 4C4G · Structure-based design of orally bioavailable pyrrolopyridine inhibitors of the mitotic… · 7RO A1796 · binds LYS529, ILE531, GLY532, VAL539, GLN541, ALA551, LYS553, LEU575 and 13 more
- 4C4H · Structure-based design of orally bioavailable pyrrolopyridine inhibitors of the mitotic… · 7RO A1795 · binds ILE531, GLY532, VAL539, GLN541, ALA551, LYS553, LEU575, ILE586 and 11 more
- 5AP5 · Naturally Occurring Mutations in the MPS1 Gene Predispose Cells to Kinase Inhibitor Drug… · 7RO A1795 · binds ILE531, GLY532, VAL539, GLN541, ALA551, LYS553, LEU575, ILE586 and 10 more
- 4C4G · Structure-based design of orally bioavailable pyrrolopyridine inhibitors of the mitotic… · 7RO A1796 · binds LYS529, ILE531, GLY532, VAL539, GLN541, ALA551, LYS553, LEU575 and 13 more
- 4C4H · Structure-based design of orally bioavailable pyrrolopyridine inhibitors of the mitotic… · 7RO A1795 · binds ILE531, GLY532, VAL539, GLN541, ALA551, LYS553, LEU575, ILE586 and 11 more
- 5AP5 · Naturally occurring mutations in the MPS1 gene predispose cells to kinase inhibitor drug… · 7RO A1795 · binds ILE531, GLY532, VAL539, GLN541, ALA551, LYS553, LEU575, ILE586 and 10 more
Residues it binds most
ILE 6, GLY 6, LEU 6, ALA 6, MET 6, LYS 6, ASN 6, ASP 6, CYS 6, GLN 6 (residue and the binding sites it lines).
Found with
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