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Ligand · 7QU

7QU · 1-(4-{(1s,3s)-3-[4-amino-5-(3-amino-4-chlorophenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl}piperazin-1-yl)ethan-1-one

7QU, 1-(4-{(1s,3s)-3-[4-amino-5-(3-amino-4-chlorophenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl}piperazin-1-yl)ethan-1-one (C22 H26 Cl N7 O, 439.9 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
7QU
Formula
C22 H26 Cl N7 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

7QU in 2 structures; the first of them:

  • 7RUN · Crystal structure of phosphorylated RET tyrosine kinase domain complexed with a… · 7QU A1102 · binds LEU730, GLY731, GLU732, GLY733, VAL738, ALA756, LYS758, GLU775 and 12 more
  • 7RUN · Crystal structure of phosphorylated ret tyrosine kinase domain complexed with a… · 7QU A1102 · binds LEU730, GLY733, VAL738, ALA756, LYS758, GLU775, LEU779, VAL804 and 7 more

Residues it binds most

LEU 4, GLU 4, ALA 4, VAL 4, SER 4, GLY 4, ARG 4, ASP 4, LYS 4, TYR 4 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion

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