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Ligand · 7PX

7PX · (2~{R},4~{R})-4-[[(2~{S},4~{S})-4-fluoranylpyrrolidin-2-yl]carbonylamino]-1-(2-methylpropanoyl)-~{N}-[[4-(2-phenylethynyl)phenyl]methyl]pyrrolidine-2-carboxamide

7PX, (2~{R},4~{R})-4-[[(2~{S},4~{S})-4-fluoranylpyrrolidin-2-yl]carbonylamino]-1-(2-methylpropanoyl)-~{N}-[[4-(2-phenylethynyl)phenyl]methyl]pyrrolidine-2-carboxamide (C29 H33 F N4 O3, 504.6 g/mol), in the MolNFT structures on GenesisL1…

Component
7PX
Formula
C29 H33 F N4 O3
Class
ligand
Structures
2
PDB entries
2

Binding sites

7PX in 2 structures; the first of them:

  • 7PHJ · LpxC Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel… · 7PX A402 · binds LEU18, LEU62, CYS63, THR76, GLU78, HIS79, PHE161, THR191 and 16 more
  • 7PHN · LpxC Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel… · 7PX A302 · binds LEU18, HIS19, MET62, SER63, THR75, GLU77, HIS78, PHE160 and 17 more

Residues it binds most

HIS 2, PHE 2, LEU 2, GLY 2, THR 2, ALA 2, SER 2, VAL 2, ASP 2, CYS 1 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion

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