GL1X · GenesisL1 explorer

Ligand · 7N1

7N1 · 5-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl) ethoxy]-4-fluorophenoxy}-7-fluoronaphthalene-2-carbonitrile

7N1, 5-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl) ethoxy]-4-fluorophenoxy}-7-fluoronaphthalene-2-carbonitrile (C23 H15 F2 N3 O4, 435.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (3 PDB entries). Every binding…

Component
7N1
Formula
C23 H15 F2 N3 O4
Class
ligand
Structures
4
PDB entries
3

Binding sites

7N1 in 4 structures; the first of them:

  • 5TW3 · Crystal Structure of HIV-1 Reverse Transcriptase in Complex with… · 7N1 A601 · binds PRO95, LEU100, LYS101, LYS102, LYS103, VAL106, VAL108, VAL179 and 11 more
  • 8STR · Crystal Structure of HIV-1 Reverse Transcriptase (Y181C) varient in Complex with… · 7N1 A601 · binds PRO95, LEU100, LYS101, LYS102, LYS103, VAL106, VAL108, VAL179 and 10 more
  • 8STS · Crystal Structure of HIV-1 Reverse Transcriptase (Y181C, V106A) varient in Complex with… · 7N1 C601 · binds PRO95, LEU100, LYS101, LYS102, LYS103, ALA106, VAL108, VAL179 and 12 more
  • 5TW3 · Crystal structure of HIV-1 reverse transcriptase in complex with 5-(2… · 7N1 A601 · binds PRO95, LEU100, LYS101, LYS102, LYS103, VAL106, VAL108, VAL179 and 8 more

Residues it binds most

VAL 5, LYS 5, PRO 5, TYR 5, LEU 5, GLY 5, PHE 5, TRP 5, HIS 4, CYS 3 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.