GL1X · GenesisL1 explorer

Ligand · 7LW

7LW · (5~{R},13~{S},17~{S})-5-[(3,4-dichlorophenyl)methyl]-8-methyl-13-[(4-methylsulfonylphenyl)methyl]-1,4,8,12, 16-pentazatricyclo[15.8.1.0^{20,25}]hexacosa-20,22,24-triene-3,7,15,26-tetrone

7LW, (5~{R},13~{S},17~{S})-5-[(3,4-dichlorophenyl)methyl]-8-methyl-13-[(4-methylsulfonylphenyl)methyl]-1,4,8,12, 16-pentazatricyclo[15.8.1.0^{20,25}]hexacosa-20,22,24-triene-3,7,15,26-tetrone (C37 H43 Cl2 N5 O6 S, 756.7 g/mol), in the…

Component
7LW
Formula
C37 H43 Cl2 N5 O6 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

7LW in 2 structures; the first of them:

  • 5MEV · MCL1 Fab complex in complex with compound 21 · 7LW A401 · binds HIS224, ALA227, PHE228, MET231, VAL249, MET250, HIS252, VAL253 and 6 more
  • 5MEV · MCL1 Fab complex in complex with compound 21 · 7LW A401 · binds HIS224, ALA227, PHE228, MET231, VAL249, MET250, HIS252, VAL253 and 4 more

Residues it binds most

HIS 2, MET 2, PHE 2, VAL 2, ALA 2, ARG 2, ASP 2, THR 2, LEU 1, SER 1 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.