Ligand · 7L2

7L2 · [[[(3~{A}~{R},4~{R},6~{R},6~{A}~{R})-4-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-7-ium-9-yl)-2,2-dimethyl-3~{A},4,6,6~{A}-tetrahydrofuro[3,4-D][1, 3]dioxol-6-yl]methoxy-oxidanyl-phosphoryl]oxy-sulfanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate

7L2, [[[(3~{A}~{R},4~{R},6~{R},6~{A}~{R})-4-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-7-ium-9-yl)-2,2-dimethyl-3~{A},4,6,6~{A}-tetrahydrofuro[3,4-D][1, 3]dioxol-6-yl]methoxy-oxidanyl-phosphoryl]oxy-sulfanyl-phosphoryl]…

Component: 7L2
Formula: C24 H34 N10 O17 P3 S +1
Class: ligand
Structures: 3
PDB entries: 2

Binding sites

7L2 in 3 structures; the first of them:

5M81 · Translation initiation factor 4E in complex with (SP)-iPr-m7GppSpG mRNA 5' cap analog · 7L2 A301 · binds PHE48, ASN50, ASP51, LYS52, LYS54, THR55, TRP56, ASN59 and 7 more
5M80 · Translation initiation factor 4E in complex with (rp)-ipr-M7GPPSPG mRNA 5' cap analog · 7L2 A301 · binds PHE48, ASN50, ASP51, LYS52, LYS54, THR55, TRP56, GLN57 and 6 more
5M81 · Translation initiation factor 4E in complex with (sp)-ipr-M7GPPSPG mRNA 5' cap analog · 7L2 A301 · binds PHE48, ASN50, ASP51, LYS52, LYS54, THR55, TRP56, ASN59 and 7 more

Residues it binds most

LYS 10, TRP 10, ASN 10, ARG 10, ASP 10, MET 10, THR 10, GLU 8, PHE 6, GLN 2 (residue and the binding sites it lines).

Found with

GOL · Glycerol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.