Ligand · 7KU

7KU · 1-{(3R)-3-[(7H-pyrrolo[2,3-d]pyrimidin-4-yl) amino]piperidin-1-yl}propan-1-one

7KU, 1-{(3R)-3-[(7H-pyrrolo[2,3-d]pyrimidin-4-yl) amino]piperidin-1-yl}propan-1-one (C14 H19 N5 O, 273.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å…

Component: 7KU
Formula: C14 H19 N5 O
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

7KU in 2 structures; the first of them:

5TTS · Jak3 with covalent inhibitor 4 · 7KU A4000 · binds LEU828, GLY829, VAL836, ALA853, VAL884, MET902, GLU903, TYR904 and 7 more
5TTS · JAK3 with covalent inhibitor 4 · 7KU A4000 · binds LEU828, GLY829, ALA853, VAL884, MET902, GLU903, TYR904, LEU905 and 6 more

Residues it binds most

LEU 2, ARG 2, GLY 2, VAL 2, ALA 2, ASP 2, CYS 2, GLU 2, MET 2, TYR 2 (residue and the binding sites it lines).

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