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Ligand · 7HD

7HD · 3-((4-(6-chloro-2-(1,3-dimethyl-1H-pyrazol-4-yl)-3H-imidazo[4,5-b]pyridin-7-yl)-1H-pyrazol-1-yl)methyl)-5-methylisoxazole

7HD, 3-((4-(6-chloro-2-(1,3-dimethyl-1H-pyrazol-4-yl)-3H-imidazo[4,5-b]pyridin-7-yl)-1H-pyrazol-1-yl)methyl)-5-methylisoxazole (C19 H17 Cl N8 O, 408.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
7HD
Formula
C19 H17 Cl N8 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

7HD in 2 structures; the first of them:

  • 5AAE · Aurora A kinase bound to an imidazopyridine inhibitor (14d) · 7HD A1389 · binds ARG137, LEU139, GLY140, LYS141, GLY142, LYS143, GLY145, ASN146 and 13 more
  • 5AAE · Aurora a kinase bound to an imidazopyridine inhibitor (14D) · 7HD A1389 · binds ARG137, LEU139, GLY140, LYS141, GLY142, LYS143, GLY145, ASN146 and 13 more

Residues it binds most

LEU 2, GLY 2, LYS 2, ALA 2, ARG 2, ASN 2, GLU 2, PRO 2, TYR 2, VAL 2 (residue and the binding sites it lines).

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