GL1X · GenesisL1 explorer

Ligand · 7FX

7FX · [2,4-bis(oxidanyl)phenyl]-[(7~{S})-7-(trifluoromethyl)-6,7-dihydro-5~{H}-pyrazolo[1,5-a]pyrimidin-4-yl]methanone

7FX, [2,4-bis(oxidanyl)phenyl]-[(7~{S})-7-(trifluoromethyl)-6,7-dihydro-5~{H}-pyrazolo[1,5-a]pyrimidin-4-yl]methanone (C14 H12 F3 N3 O3, 327.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component
7FX
Formula
C14 H12 F3 N3 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

7FX in 2 structures; the first of them:

  • 5M4H · Application of Off-Rate Screening in the Identification of Novel Pan-Isoform Inhibitors… · 7FX A301 · binds LEU48, ASN51, SER52, ASP54, ALA55, LYS58, ASP93, ILE96 and 8 more
  • 5M4H · Application of off-rate screening in the identification of novel pan- isoform inhibitors… · 7FX A301 · binds LEU48, ASN51, SER52, ALA55, LYS58, ASP93, ILE96, GLY97 and 5 more

Residues it binds most

GLY 2, ASP 2, LEU 2, THR 2, ALA 2, ASN 2, ILE 2, LYS 2, MET 2, PHE 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.