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Ligand · 7FK

7FK · 15-Chloro-16,18-dihydroxy-2-methyl-3,4,7,8,9,10,11,12-octahydrobenz[c][1]azacyclohexadecine-1,13(2H,14H)-dione

7FK, 15-Chloro-16,18-dihydroxy-2-methyl-3,4,7,8,9,10,11,12-octahydrobenz[c][1]azacyclohexadecine-1,13(2H,14H)-dione (C20 H26 Cl N O4, 379.9 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…

Component
7FK
Formula
C20 H26 Cl N O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

7FK in 2 structures; the first of them:

  • 4CE1 · Hsp90 N-terminal domain bound to macrolactam analogues of radicicol. · 7FK A1215 · binds LEU34, ASN37, ALA38, ALA41, ASP79, ILE82, GLY83, MET84 and 5 more
  • 4CE1 · HSP90 N-terminal domain bound to macrolactam analogues of radicicol. · 7FK A1215 · binds LEU34, ASN37, ALA38, ALA41, ASP79, ILE82, GLY83, MET84 and 5 more

Residues it binds most

LEU 2, ALA 2, ASN 2, ASP 2, GLY 2, ILE 2, MET 2, PHE 2, THR 2 (residue and the binding sites it lines).

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