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Ligand · 7FH

7FH · 1-hydroxy-5-(trifluoromethyl)pyridine-2(1H)-thione

7FH, 1-hydroxy-5-(trifluoromethyl)pyridine-2(1H)-thione (C6 H4 F3 N O S, 195.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds most…

Component
7FH
Formula
C6 H4 F3 N O S
Class
ligand
Structures
2
PDB entries
1

Binding sites

7FH in 2 structures; the first of them:

  • 4Q8X · Crystal structure of 1-hydroxy-5-(trifluoromethyl)pyridine-2(1H)-thione bound to human… · 7FH A304 · binds GLN92, HIS94, HIS119, VAL121, PHE131, VAL143, LEU198, THR199 and 2 more
  • 4Q8X · Crystal structure of 1-hydroxy-5-(TRIFLUOROMETHYL)PYRIDINE-2(1H)- thione bound to human… · 7FH A304 · binds GLN92, HIS94, HIS119, VAL121, PHE131, VAL143, LEU198, THR199 and 2 more

Residues it binds most

HIS 2, THR 2, VAL 2, GLN 2, LEU 2, PHE 2, TRP 2 (residue and the binding sites it lines).

Found with

  • MBO · Mercuribenzoic acid
  • ZN · Zinc ion
  • DMS · Dimethyl sulfoxide

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