7F3 · (1S)-4-fluoro-1-(4-fluoro-3-pyrimidin-5-ylphenyl)-1-[2-(trifluoromethyl)pyridin-4-yl]-1H-isoindol-3-amine

Binding sites

7F3 in 2 structures; the first of them:

• 4AZY · Design and Synthesis of BACE1 Inhibitors with In Vivo Brain Reduction of beta-Amyloid… · 7F3 A1507 · binds GLY11, GLN12, GLY13, LEU30, ASP32, GLY34, SER35, ASN37 and 13 more
• 4AZY · Design and synthesis of BACE1 inhibitors with in vivo brain reduction of beta-amyloid… · 7F3 A1507 · binds GLY11, GLN12, GLY13, LEU30, ASP32, GLY34, SER35, ASN37 and 13 more

Residues it binds most

GLY 2, ASP 2, GLN 2, ILE 2, THR 2, TRP 2, ALA 2, ASN 2, LEU 2, PHE 2 (residue and the binding sites it lines).

Found with

• NA · Sodium ion
• ACT · Acetate ion