GL1X · GenesisL1 explorer

Ligand · 7AI

7AI · (1S,2R,4S)-5,6-bis(4-hydroxyphenyl)-N-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-N-(2,2,2-trifluoroethyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide

7AI, (1S,2R,4S)-5,6-bis(4-hydroxyphenyl)-N-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-N-(2,2,2-trifluoroethyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide (C33 H35 F3 N2 O6 S, 644.7 g/mol), in the MolNFT structures on GenesisL1: bound in 2…

Component
7AI
Formula
C33 H35 F3 N2 O6 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

7AI in 2 structures; the first of them:

  • 7RRX · Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with… · 7AI A601 · binds MET343, LEU346, THR347, LEU349, ALA350, GLU353, TRP383, LEU384 and 19 more
  • 7RRX · Crystal structure of the er-alpha ligand-binding domain (L372S, L536S) in complex with… · 7AI A601 · binds MET343, LEU346, THR347, LEU349, ALA350, GLU353, TRP383, LEU384 and 19 more

Residues it binds most

LEU 8, MET 8, GLU 8, PHE 8, GLY 8, VAL 8, ALA 8, ARG 8, ILE 8, THR 8 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion

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