GL1X · GenesisL1 explorer

Ligand · 7A7

7A7 · Methyl 9-[(2-fluoranyl-4-methoxy-phenyl)amino]-[1, 3]thiazolo[5,4-f]quinazoline-2-carboximidate

7A7, Methyl 9-[(2-fluoranyl-4-methoxy-phenyl)amino]-[1, 3]thiazolo[5,4-f]quinazoline-2-carboximidate (C18 H14 F N5 O2 S, 383.4 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (2 PDB entries). Every binding site with its…

Component
7A7
Formula
C18 H14 F N5 O2 S
Class
ligand
Structures
3
PDB entries
2

Binding sites

7A7 in 3 structures; the first of them:

  • 5LXD · Crystal structure of DYRK2 in complex with EHT 1610 (compound 2) · 7A7 A501 · binds ILE155, GLY156, LYS157, PHE160, VAL163, ALA176, LYS178, ILE212 and 8 more
  • 5LXD · Crystal structure of DYRK2 in complex with eht 1610 (compound 2) · 7A7 A501 · binds ILE155, GLY156, LYS157, PHE160, VAL163, ALA176, LYS178, ILE212 and 8 more
  • 6YTI · CLK1 bound with ETH1610 (cpd 17) · 7A7 A605 · binds LEU167, GLU169, PHE172, VAL175, ALA189, LYS191, PHE241, GLU242 and 10 more

Residues it binds most

ILE 4, LEU 5, GLU 5, PHE 5, LYS 5, ASP 5, VAL 5, ALA 5, GLY 5, ASN 4 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.