GL1X · GenesisL1 explorer

Ligand · 799

799 · 2-methyl-2-(4-{2-[3-methyl-1-(propan-2-yl)-1H-1,2,4-triazol-5-yl]-5,6-dihydroimidazo[1,2-D][1, 4]benzoxazepin-9-yl}-1H-pyrazol-1-yl)propanamide

799, 2-methyl-2-(4-{2-[3-methyl-1-(propan-2-yl)-1H-1,2,4-triazol-5-yl]-5,6-dihydroimidazo[1,2-D][1, 4]benzoxazepin-9-yl}-1H-pyrazol-1-yl)propanamide (C24 H28 N8 O2, 460.5 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (2…

Component
799
Formula
C24 H28 N8 O2
Class
ligand
Structures
3
PDB entries
2

Binding sites

799 in 3 structures; the first of them:

  • 5T8F · p110delta/p85alpha with taselisib (GDC-0032) · 799 A1101 · binds MET752, PRO758, TRP760, ILE777, LYS779, LEU784, ASP787, TYR813 and 10 more
  • 8EXL · Crystal structure of PI3K-alpha in complex with taselisib · 799 A1101 · binds ARG770, SER774, PRO778, TRP780, ILE800, LYS802, ASP810, TYR836 and 12 more
  • 5T8F · P110DELTA/P85ALPHA with taselisib (gdc-0032) · 799 A1101 · binds PRO758, TRP760, ILE777, LYS779, ASP787, TYR813, ILE825, GLU826 and 8 more

Residues it binds most

ILE 3, ASP 3, VAL 3, MET 3, SER 3, GLU 3, LYS 3, PHE 3, PRO 3, TRP 3 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.