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Ligand · 747

747 · (5Z)-5-[(3,5-difluoro-4-hydroxyphenyl)methylidene]-2-[(E)-(hydroxyimino)methyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one

747, (5Z)-5-[(3,5-difluoro-4-hydroxyphenyl)methylidene]-2-[(E)-(hydroxyimino)methyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one (C12 H9 F2 N3 O3, 281.2 g/mol), in the MolNFT structures on GenesisL1: bound in 11 records (8 PDB entries). Every…

Component
747
Formula
C12 H9 F2 N3 O3
Class
ligand
Structures
11
PDB entries
8

Binding sites

747 in 11 structures; the first of them:

  • 5BJO · Crystal structure of the Corn RNA aptamer in complex with DFHO, site-specific 5-iodo-U · 747 Y104 · binds G12, A14, G15, G22, G25, A11, G12, G15 and 3 more
  • 5BJP · Crystal structure of the Corn RNA aptamer in complex with DFHO, iridium hexammine soak · 747 Y104 · binds G12, A14, G15, G22, G25, A11, G12, G15 and 3 more
  • 7KVV · Crystal structure of Squash RNA aptamer in complex with DFHBI-1T · 747 D302 · binds G13, G14, U15, U39, A40, A48, A69, A70
  • 8EYV · Structure of Beetroot dimer bound to DFHO · 747 A104 · binds A16, G17, U26, A34, G35, A37, U38
  • 8F0N · Wobble Beetroot (A16U-U38G) dimer bound to DFHO · 747 B103 · binds U16, G17, U26, A34, A37, G38
  • 8FHZ · Structure of Lettuce aptamer bound to DFHO · 747 A107 · binds DG10, DA11, DT12, DC17, DG18, DC20, DG25, DG26 and 2 more
  • 8FI1 · Structure of Lettuce C20G bound to DFHO · 747 A106 · binds DG10, DA11, DC17, DG18, DG20, DG25, DG26, DG44
  • 8FI7 · Structure of Lettuce C20T bound to DFHO · 747 A106 · binds DG10, DA11, DT12, DC17, DG18, DT20, DG25, DG26 and 2 more
  • 5BJO · Crystal structure of the corn RNA aptamer in complex with dfho, site- specific 5-iodo-U · 747 Y104 · binds G12, A14, G15, G22, G25, A11, G12, G15 and 3 more
  • 5BJP · Crystal structure of the corn RNA aptamer in complex with dfho, iridium hexammine soak · 747 Y104 · binds G12, A14, G15, G22, G25, A11, G12, G15 and 3 more
  • 7KVV · Crystal structure of squash RNA aptamer in complex with dfhbi-1T · 747 D302 · binds G13, G14, U15, U39, A40, A48, A69, A70

Residues it binds most

G 10, A 10, DG 3, U 6, DC 3, DA 3, DT 2 (residue and the binding sites it lines).

Found with

  • K · Potassium ion
  • MG · Magnesium ion
  • IR · Iridium ion
  • DMS · Dimethyl sulfoxide

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