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Ligand · 736

736 · (11S)-8-chloro-11-[1-(methylsulfonyl)piperidin-4-yl]-6-piperazin-1-yl-11H-benzo[5,6]cyclohepta[1,2-b]pyridine

736, (11S)-8-chloro-11-[1-(methylsulfonyl)piperidin-4-yl]-6-piperazin-1-yl-11H-benzo[5,6]cyclohepta[1,2-b]pyridine (C24 H29 Cl N4 O2 S, 473.0 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component
736
Formula
C24 H29 Cl N4 O2 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

736 in 2 structures; the first of them:

  • 2BED · Structure of FPT bound to inhibitor SCH207736 · 736 B2001 · binds LYS164, ASN165, TYR166, HIS201, CYS95, LEU96, TRP102, TRP106 and 5 more
  • 2BED · Structure of fpt bound to inhibitor SCH207736 · 736 B2001 · binds LYS164, ASN165, TYR166, HIS201, CYS95, LEU96, TRP102, TRP106 and 5 more

Residues it binds most

TYR 2, ASP 2, CYS 2, TRP 2, ASN 2, HIS 2, LEU 2, LYS 2 (residue and the binding sites it lines).

Found with

  • FPP · Farnesyl diphosphate
  • ZN · Zinc ion

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