GL1X · GenesisL1 explorer

Ligand · 70I

70I · 1-[4-[4-[[3,5-bis(chloranyl)-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]amino]pyrimido[5,4-d]pyrimidin-6-yl]piperazin-1-yl]-4-(3-fluoranylazetidin-1-yl)butan-1-one

70I, 1-[4-[4-[[3,5-bis(chloranyl)-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]amino]pyrimido[5,4-d]pyrimidin-6-yl]piperazin-1-yl]-4-(3-fluoranylazetidin-1-yl)butan-1-one (C29 H28 Cl2 F N11 O2, 652.5 g/mol), in the MolNFT structures on…

Component
70I
Formula
C29 H28 Cl2 F N11 O2
Class
ligand
Structures
1
PDB entries
1

Binding sites

70I in 1 structure; the first of them:

  • 7PCD · HER2 in complex with a covalent inhibitor · 70I A1101 · binds LEU726, VAL734, ALA751, LYS753, ALA771, MET774, SER783, ARG784 and 12 more

Residues it binds most

LEU 1, ALA 1, ARG 1, ASP 1, MET 1, THR 1, CYS 1, GLN 1, LYS 1, PHE 1 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.